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The A(2) Adenosine Receptor: Guanine Nucleotide Modulation of Agonist Binding Is Enhanced by Proteolysis

Agonist binding to the A(2) adenosine receptor (A(2)AR) and its regulation by guanine nucleotides was studied using the newly developed radioligand (125)l-2-[4-(2-{2-[(4-ammnophenyl)methylcarbonylamino]ethylaminnocarbonyl}ethyl)phenyl]ethylamino-5′-N-ethylcarboxamidoadenosine ((125)1-PAPA-APEC) and...

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Bibliographische Detailangaben
Hauptverfasser: NANOFF, CHRISTIAN, JACOBSON, KENNETH A., STILES, GARY L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1991
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3463105/
https://ncbi.nlm.nih.gov/pubmed/1899902
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