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Demonstration of Distinct Agonist and Antagonist Conformations of the A(1) Adenosine Receptor

A(1) adenosine receptor-binding subunits can be visualized using high affinity antagonist and agonist photoaffinity radioligands. In the present study, we examined whether agonists and antagonists bind to the same receptor-binding subunit and if agonists and antagonists induce different conformation...

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Main Authors: Barrington, William W., Jacobson, Kenneth A., Stiles, Gary L.
格式: Artigo
語言:Inglês
出版: 1989
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3478959/
https://ncbi.nlm.nih.gov/pubmed/2753906
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