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A postprandial FGF19‐SHP‐LSD1 regulatory axis mediates epigenetic repression of hepatic autophagy

Lysosome‐mediated autophagy is essential for cellular survival and homeostasis upon nutrient deprivation, but is repressed after feeding. Despite the emerging importance of transcriptional regulation of autophagy by nutrient‐sensing factors, the role for epigenetic control is largely unexplored. Her...

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Detalhes bibliográficos
Publicado no:EMBO J
Main Authors: Byun, Sangwon, Kim, Young‐Chae, Zhang, Yang, Kong, Bo, Guo, Grace, Sadoshima, Junichi, Ma, Jian, Kemper, Byron, Kemper, Jongsook Kim
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5470039/
https://ncbi.nlm.nih.gov/pubmed/28446510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201695500
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