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A postprandial FGF19‐SHP‐LSD1 regulatory axis mediates epigenetic repression of hepatic autophagy

Lysosome‐mediated autophagy is essential for cellular survival and homeostasis upon nutrient deprivation, but is repressed after feeding. Despite the emerging importance of transcriptional regulation of autophagy by nutrient‐sensing factors, the role for epigenetic control is largely unexplored. Her...

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Detalles Bibliográficos
Publicado en:EMBO J
Autores principales: Byun, Sangwon, Kim, Young‐Chae, Zhang, Yang, Kong, Bo, Guo, Grace, Sadoshima, Junichi, Ma, Jian, Kemper, Byron, Kemper, Jongsook Kim
Formato: Artigo
Lenguaje:Inglês
Publicado: John Wiley and Sons Inc. 2017
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5470039/
https://ncbi.nlm.nih.gov/pubmed/28446510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201695500
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