Hepatic Diacylglycerol-Associated Protein Kinase Cε Translocation Links Hepatic Steatosis to Hepatic Insulin Resistance in Humans

Hepatic lipid accumulation has been implicated in the development of insulin resistance, but translational evidence in humans is limited. We investigated the relationship between liver fat and tissue-specific insulin sensitivity in 133 obese subjects. Although the presence of hepatic steatosis in ob...

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發表在:Cell Rep
Main Authors: ter Horst, Kasper W., Gilijamse, Pim W., Versteeg, Ruth I., Ackermans, Mariette T., Nederveen, Aart J., la Fleur, Susanne E., Romijn, Johannes A., Nieuwdorp, Max, Zhang, Dongyan, Samuel, Varman T., Vatner, Daniel F., Petersen, Kitt F., Shulman, Gerald I., Serlie, Mireille J.
格式: Artigo
語言:Inglês
出版: Cell Press 2017
主題:
Report
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5469939/
https://ncbi.nlm.nih.gov/pubmed/28591572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2017.05.035
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