Hepatic Diacylglycerol-Associated Protein Kinase Cε Translocation Links Hepatic Steatosis to Hepatic Insulin Resistance in Humans

Hepatic lipid accumulation has been implicated in the development of insulin resistance, but translational evidence in humans is limited. We investigated the relationship between liver fat and tissue-specific insulin sensitivity in 133 obese subjects. Although the presence of hepatic steatosis in ob...

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Gepubliceerd in:Cell Rep
Hoofdauteurs: ter Horst, Kasper W., Gilijamse, Pim W., Versteeg, Ruth I., Ackermans, Mariette T., Nederveen, Aart J., la Fleur, Susanne E., Romijn, Johannes A., Nieuwdorp, Max, Zhang, Dongyan, Samuel, Varman T., Vatner, Daniel F., Petersen, Kitt F., Shulman, Gerald I., Serlie, Mireille J.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Cell Press 2017
Onderwerpen:
Report
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5469939/
https://ncbi.nlm.nih.gov/pubmed/28591572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2017.05.035
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