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Estimating the causal influence of body mass index on risk of Parkinson disease: A Mendelian randomisation study

BACKGROUND: Both positive and negative associations between higher body mass index (BMI) and Parkinson disease (PD) have been reported in observational studies, but it has been difficult to establish causality because of the possibility of residual confounding or reverse causation. To our knowledge,...

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Detalhes bibliográficos
Publicado no:PLoS Med
Main Authors: Noyce, Alastair J., Kia, Demis A., Hemani, Gibran, Nicolas, Aude, Price, T. Ryan, De Pablo-Fernandez, Eduardo, Haycock, Philip C., Lewis, Patrick A., Foltynie, Thomas, Davey Smith, George, Schrag, Anette, Lees, Andrew J., Hardy, John, Singleton, Andrew, Nalls, Mike A., Pearce, Neil, Lawlor, Debbie A., Wood, Nicholas W.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5469450/
https://ncbi.nlm.nih.gov/pubmed/28609445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pmed.1002314
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