Estimating the causal influence of body mass index on risk of Parkinson disease: A Mendelian randomisation study

BACKGROUND: Both positive and negative associations between higher body mass index (BMI) and Parkinson disease (PD) have been reported in observational studies, but it has been difficult to establish causality because of the possibility of residual confounding or reverse causation. To our knowledge,...

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Vydáno v:PLoS Med
Hlavní autoři: Noyce, Alastair J., Kia, Demis A., Hemani, Gibran, Nicolas, Aude, Price, T. Ryan, De Pablo-Fernandez, Eduardo, Haycock, Philip C., Lewis, Patrick A., Foltynie, Thomas, Davey Smith, George, Schrag, Anette, Lees, Andrew J., Hardy, John, Singleton, Andrew, Nalls, Mike A., Pearce, Neil, Lawlor, Debbie A., Wood, Nicholas W.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2017
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5469450/
https://ncbi.nlm.nih.gov/pubmed/28609445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pmed.1002314
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