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Modeling Combined Immunosuppressive and Anti-inflammatory Effects of Dexamethasone and Naproxen in Rats Predicts the Steroid-Sparing Potential of Naproxen

Dexamethasone (DEX), a widely prescribed corticosteroid, has long been the cornerstone of the treatment of inflammation and immunologic dysfunctions in rheumatoid arthritis. Corticosteroids are frequently used in combination with other antirheumatic agents such as nonsteroidal anti-inflammatory drug...

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Bibliographic Details
Published in:Drug Metab Dispos
Main Authors: Li, Xiaonan, DuBois, Debra C., Song, Dawei, Almon, Richard R., Jusko, William J., Chen, Xijing
Format: Artigo
Language:Inglês
Published: The American Society for Pharmacology and Experimental Therapeutics 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5469402/
https://ncbi.nlm.nih.gov/pubmed/28416614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.117.075614
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