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Modeling Combined Immunosuppressive and Anti-inflammatory Effects of Dexamethasone and Naproxen in Rats Predicts the Steroid-Sparing Potential of Naproxen

Dexamethasone (DEX), a widely prescribed corticosteroid, has long been the cornerstone of the treatment of inflammation and immunologic dysfunctions in rheumatoid arthritis. Corticosteroids are frequently used in combination with other antirheumatic agents such as nonsteroidal anti-inflammatory drug...

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Bibliografiska uppgifter
I publikationen:Drug Metab Dispos
Huvudupphovsmän: Li, Xiaonan, DuBois, Debra C., Song, Dawei, Almon, Richard R., Jusko, William J., Chen, Xijing
Materialtyp: Artigo
Språk:Inglês
Publicerad: The American Society for Pharmacology and Experimental Therapeutics 2017
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5469402/
https://ncbi.nlm.nih.gov/pubmed/28416614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.117.075614
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