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Distinct Roles of Vaccinia Virus NF-κB Inhibitor Proteins A52, B15, and K7 in the Immune Response

Poxviruses use a complex strategy to escape immune control, by expressing immunomodulatory proteins that could limit their use as vaccine vectors. To test the role of poxvirus NF-κB pathway inhibitors A52, B15, and K7 in immunity, we deleted their genes in an NYVAC (New York vaccinia virus) strain t...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Di Pilato, Mauro, Mejías-Pérez, Ernesto, Sorzano, Carlos Oscar S., Esteban, Mariano
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5469261/
https://ncbi.nlm.nih.gov/pubmed/28424281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00575-17
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