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Light-activated Ru(II) complexes for caging cytochrome P450 inhibitors
New Ru(II)-caged abiraterone complexes were synthesized that exhibit strong absorption in the visible region and release the steroidal CYP17A1 inhibitor abiraterone upon exposure to low energy visible light in buffer and prostate cancer cells. Photoinduced release results in abiraterone binding to i...
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| Pubblicato in: | Chem Commun (Camb) |
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| Autori principali: | , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5468790/ https://ncbi.nlm.nih.gov/pubmed/28304025 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7cc01459g |
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