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Caging the Uncageable: Using Metal Complex Release for Photochemical Control over Irreversible Inhibition

Photochemical control over irreversible inhibition was shown using Ru(II)-caged inhibitors of cathepsin L. Levels of control were dependent on where the Ru(II) complex was attached to the organic inhibitor, reaching >10:1 with optimal placement. A new strategy for photoreleasing Ru(II) fragments...

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Bibliografiska uppgifter
I publikationen:Chem Commun (Camb)
Huvudupphovsmän: Huisman, Matthew, White, Jessica K., Lewalski, Veronica G., Podgorski, Izabela, Turro, Claudia, Kodanko, Jeremy J.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2016
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5076553/
https://ncbi.nlm.nih.gov/pubmed/27711349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c6cc07083c
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