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Affnity-Enhanced Luminescent Re(I)- and Ru(II)-Based Inhibitors of the Cysteine Protease Cathepsin L
Two new Re(I)- and Ru(II)-based inhibitors were synthesized with the formulas [Re(phen)(CO)(3)(1)](OTf) (7; phen = 1,10-phenanthroline, OTf = trifluoromethanesulfonate) and [Ru(bpy)(2)(2)](Cl)(2) (8; bpy = 2,2′-bipyridine), where 1 and 2 are the analogues of CLIK-148, an epoxysuccinyl-based cysteine...
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| Publicado no: | Inorg Chem |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6034508/ https://ncbi.nlm.nih.gov/pubmed/29882662 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.inorgchem.8b00978 |
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