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Distinct activation modes of the Relaxin Family Peptide Receptor 2 in response to insulin-like peptide 3 and relaxin

Relaxin family peptide receptor 2 (RXFP2) is a GPCR known for its role in reproductive function. It is structurally related to the human relaxin receptor RXFP1 and can be activated by human gene-2 (H2) relaxin as well as its cognate ligand insulin-like peptide 3 (INSL3). Both receptors possess an N-...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Bruell, Shoni, Sethi, Ashish, Smith, Nicholas, Scott, Daniel J., Hossain, Mohammed Akhter, Wu, Qing-Ping, Guo, Zhan-Yun, Petrie, Emma J., Gooley, Paul R., Bathgate, Ross A. D.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5468325/
https://ncbi.nlm.nih.gov/pubmed/28607406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-03638-4
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