Investigation of Interactions at the Extracellular Loops of the Relaxin Family Peptide Receptor 1 (RXFP1)

Relaxin, an emerging pharmaceutical treatment for acute heart failure, activates the relaxin family peptide receptor (RXFP1), which is a class A G-protein-coupled receptor. In addition to the classic transmembrane (TM) domain, RXFP1 possesses a large extracellular domain consisting of 10 leucine-ric...

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Vydáno v:J Biol Chem
Hlavní autoři: Diepenhorst, Natalie A., Petrie, Emma J., Chen, Catherine Z., Wang, Amy, Hossain, Mohammed Akhter, Bathgate, Ross A. D., Gooley, Paul R.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2014
Témata:
Signal Transduction
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4263891/
https://ncbi.nlm.nih.gov/pubmed/25352603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.600882
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