Elucidation of relaxin-3 binding interactions in the extracellular loops of RXFP3

Relaxin-3 is a highly conserved neuropeptide in vertebrate species and binds to the Class A G protein-coupled receptor (GPCR) RXFP3. Relaxin-3 is involved in a wide range of behaviors, including feeding, stress responses, arousal, and cognitive processes and therefore targeting of RXFP3 may be relev...

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Autori principali: Bathgate, Ross A. D., Oh, Maria H. Y., Ling, W. J. Jason, Kaas, Quentin, Hossain, M. Akhter, Gooley, Paul R., Rosengren, K. Johan
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2013
Soggetti:
Endocrinology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3579193/
https://ncbi.nlm.nih.gov/pubmed/23440673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fendo.2013.00013
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