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Binding conformation and determinants of a single-chain peptide antagonist at the relaxin-3 receptor RXFP3
The neuropeptide relaxin-3 and its receptor relaxin family peptide receptor-3 (RXFP3) play key roles in modulating behavior such as memory and learning, food intake, and reward seeking. A linear relaxin-3 antagonist (R3 B1-22R) based on a modified and truncated relaxin-3 B-chain was recently develop...
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| Pubblicato in: | J Biol Chem |
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| Autori principali: | , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Biochemistry and Molecular Biology
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6187623/ https://ncbi.nlm.nih.gov/pubmed/30131342 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.002611 |
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