Sortilin-Related Receptor Expression in Human Neural Stem Cells Derived from Alzheimer's Disease Patients Carrying the APOE Epsilon 4 Allele

Alzheimer's disease (AD) is the most common form of dementia in the elderly; important risk factors are old age and inheritance of the apolipoprotein E4 (APOE4) allele. Changes in amyloid precursor protein (APP) binding, trafficking, and sorting may be important AD causative factors. Secretase-...

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Vydáno v:Neural Plast
Hlavní autoři: Zollo, Alen, Allen, Zoe, Rasmussen, Helle F., Iannuzzi, Filomena, Shi, Yichen, Larsen, Agnete, Maier, Thorsten J., Matrone, Carmela
Médium: Artigo
Jazyk:Inglês
Vydáno: Hindawi 2017
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5467336/
https://ncbi.nlm.nih.gov/pubmed/28634550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2017/1892612
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