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Accuracy of imputation to infer unobserved APOE epsilon alleles in genome-wide genotyping data
Apolipoprotein E, encoded by APOE, is the main apoprotein for catabolism of chylomicrons and very low density lipoprotein. Two common single-nucleotide polymorphisms (SNPs) in APOE, rs429358 and rs7412, determine the three epsilon alleles that are established genetic risk factors for late-onset Alzh...
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| Главные авторы: | , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Nature Publishing Group
2014
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4169533/ https://ncbi.nlm.nih.gov/pubmed/24448547 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ejhg.2013.308 |
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