Accuracy of imputation to infer unobserved APOE epsilon alleles in genome-wide genotyping data

Apolipoprotein E, encoded by APOE, is the main apoprotein for catabolism of chylomicrons and very low density lipoprotein. Two common single-nucleotide polymorphisms (SNPs) in APOE, rs429358 and rs7412, determine the three epsilon alleles that are established genetic risk factors for late-onset Alzh...

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Bibliographische Detailangaben
Hauptverfasser: Radmanesh, Farid, Devan, William J, Anderson, Christopher D, Rosand, Jonathan, Falcone, Guido J
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2014
Schlagworte:
Short Report
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4169533/
https://ncbi.nlm.nih.gov/pubmed/24448547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ejhg.2013.308
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