Sortilin-Related Receptor Expression in Human Neural Stem Cells Derived from Alzheimer's Disease Patients Carrying the APOE Epsilon 4 Allele

Alzheimer's disease (AD) is the most common form of dementia in the elderly; important risk factors are old age and inheritance of the apolipoprotein E4 (APOE4) allele. Changes in amyloid precursor protein (APP) binding, trafficking, and sorting may be important AD causative factors. Secretase-...

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Detalhes bibliográficos
Publicado no:Neural Plast
Main Authors: Zollo, Alen, Allen, Zoe, Rasmussen, Helle F., Iannuzzi, Filomena, Shi, Yichen, Larsen, Agnete, Maier, Thorsten J., Matrone, Carmela
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5467336/
https://ncbi.nlm.nih.gov/pubmed/28634550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2017/1892612
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