Biased agonism and allosteric modulation of G protein‐coupled receptor 183 – a 7TM receptor also known as Epstein–Barr virus‐induced gene 2

BACKGROUND AND PURPOSE: The GPCR Epstein–Barr virus‐induced gene 2 (EBI2, also known as GPR183) is activated by oxysterols and plays a pivotal role in the regulation of B cell migration during immune responses. While the molecular basis of agonist binding has been addressed in several studies, the c...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Br J Pharmacol
Main Authors: Daugvilaite, Viktorija, Madsen, Christian Medom, Lückmann, Michael, Echeverria, Clara Castello, Sailer, Andreas Walter, Frimurer, Thomas Michael, Rosenkilde, Mette Marie, Benned‐Jensen, Tau
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2017
Teme:
Research Papers
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5466542/
https://ncbi.nlm.nih.gov/pubmed/28369721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13801
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