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Catalytic promiscuity of ancestral esterases and hydroxynitrile lyases
Catalytic promiscuity is a useful, but accidental, enzyme property, so finding catalytically promiscuous enzymes in nature is inefficient. Some ancestral enzymes were branch points in the evolution of new enzymes and are hypothesized to have been promiscuous. To test the hypothesis that ancestral en...
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| Published in: | J Am Chem Soc |
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| Main Authors: | , , , , , , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2016
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5466365/ https://ncbi.nlm.nih.gov/pubmed/26736133 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.5b12209 |
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