Distinct structural mechanisms determine substrate affinity and kinase activity of protein kinase Cα

Por Lee, Sangbae, Devamani, Titu, Song, Hyun Deok, Sandhu, Manbir, Larsen, Adrien, Sommese, Ruth, Jain, Abhinandan, Vaidehi, Nagarajan, Sivaramakrishnan, Sivaraj
Publicado no J Biol Chem (2017)

Evolution of a Catalytic Mechanism

Por Rauwerdink, Alissa, Lunzer, Mark, Devamani, Titu, Jones, Bryan, Mooney, Joanna, Zhang, Zhi-Jun, Xu, Jian-He, Kazlauskas, Romas J., Dean, Antony M.
Publicado no Mol Biol Evol (2016)

Catalytic promiscuity of ancestral esterases and hydroxynitrile lyases

Por Devamani, Titu, Rauwerdink, Alissa M., Lun-zer, Mark, Jones, Bryan J., Mooney, Joanna L., Tan, Maxilmilien Alaric O., Zhang, Zhi-Jun, Xu, Jian-He, Dean, Antony M., Kazlauskas, Romas J.
Publicado no J Am Chem Soc (2016)