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Tetherin/BST-2: Restriction Factor or Immunomodulator?

Cell-mediated immune (CMI) responses are critical for the control of HIV-1 infection and their importance was highlighted by the existence of viral proteins, particularly Vpu and Nef, that antagonize these responses. Pandemic HIV-1 Vpu counteracts Tetherin/BST-2, a host factor that could prevent the...

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Publicat a:Curr HIV Res
Autors principals: Li, Sam X., Barrett, Bradley S., Guo, Kejun, Santiago, Mario L.
Format: Artigo
Idioma:Inglês
Publicat: 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5466165/
https://ncbi.nlm.nih.gov/pubmed/26957198
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