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Tetherin/BST-2 promotes dendritic cell activation and function during acute retrovirus infection

Tetherin/BST-2 is a host restriction factor that inhibits retrovirus release from infected cells in vitro by tethering nascent virions to the plasma membrane. However, contradictory data exists on whether Tetherin inhibits acute retrovirus infection in vivo. Previously, we reported that Tetherin-med...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Li, Sam X., Barrett, Bradley S., Guo, Kejun, Kassiotis, George, Hasenkrug, Kim J., Dittmer, Ulf, Gibbert, Kathrin, Santiago, Mario L.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4742778/
https://ncbi.nlm.nih.gov/pubmed/26846717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep20425
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