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Tetherin/BST-2 promotes dendritic cell activation and function during acute retrovirus infection

Tetherin/BST-2 is a host restriction factor that inhibits retrovirus release from infected cells in vitro by tethering nascent virions to the plasma membrane. However, contradictory data exists on whether Tetherin inhibits acute retrovirus infection in vivo. Previously, we reported that Tetherin-med...

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Publicat a:Sci Rep
Autors principals: Li, Sam X., Barrett, Bradley S., Guo, Kejun, Kassiotis, George, Hasenkrug, Kim J., Dittmer, Ulf, Gibbert, Kathrin, Santiago, Mario L.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4742778/
https://ncbi.nlm.nih.gov/pubmed/26846717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep20425
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