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Interferon-alpha treatment inhibits acute Friend retrovirus replication primarily through the antiviral effector molecule Apobec3
Therapeutic administration of IFN-α in clinical trials significantly reduced HIV-1 plasma viral load and HTLV-I proviral load in infected patients. The mechanism may involve the concerted action of multiple antiretroviral effectors collectively known as ‘restriction factors’, which could vary in rel...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3654153/ https://ncbi.nlm.nih.gov/pubmed/23315078 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1202920 |
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