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A Single Nucleotide Polymorphism in Tetherin Promotes Retrovirus Restriction In Vivo

Tetherin is a membrane protein of unusual topology expressed from rodents to humans that accumulates enveloped virus particles on the surface of infected cells. However, whether this ‘tethering’ activity promotes or restricts retroviral spread during acute retrovirus infection in vivo is controversi...

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Detalhes bibliográficos
Main Authors: Barrett, Bradley S., Smith, Diana S., Li, Sam X., Guo, Kejun, Hasenkrug, Kim J., Santiago, Mario L.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3310811/
https://ncbi.nlm.nih.gov/pubmed/22457621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1002596
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