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Reassessment of murine APOBEC1 as a retrovirus restriction factor in vivo

APOBEC1 is a cytidine deaminase involved in cholesterol metabolism that has been linked to retrovirus restriction, analogous to the evolutionarily-related APOBEC3 proteins. In particular, murine APOBEC1 was shown to inhibit Friend retrovirus (FV) in vitro, generating high levels of C-to-T and G-to-A...

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Detalhes bibliográficos
Publicado no:Virology
Main Authors: Barrett, Bradley S., Guo, Kejun, Harper, Michael S., Li, Sam X., Heilman, Karl J., Davidson, Nicholas O., Santiago, Mario L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4430097/
https://ncbi.nlm.nih.gov/pubmed/25303118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2014.09.006
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