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Ribonuclease L is not critical for innate restriction and adaptive immunity against Friend retrovirus infection
Ribonuclease L (RNase L) is a Type I Interferon regulated factor that can significantly inhibit retroviruses in vitro and may activate cytoplasmic sensing pathways to augment adaptive immunity. However, the antiretroviral activity of RNase L remains to be validated in vivo. We investigated the role...
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Main Authors: | , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2013
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3866974/ https://ncbi.nlm.nih.gov/pubmed/23725696 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2013.05.009 |
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