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Genome Packaging Sense Is Controlled by the Efficiency of the Nick Site in the Right-End Replication Origin of Parvoviruses Minute Virus of Mice and LuIII
The parvovirus minute virus of mice (MVM) packages predominantly negative-sense single strands, while its close relative LuIII encapsidates strands of both polarities with equal efficiency. Using genomic chimeras and mutagenesis, we show that the ability to package positive strands maps not, as orig...
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| Main Authors: | , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Society for Microbiology
2005
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| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC546602/ https://ncbi.nlm.nih.gov/pubmed/15681430 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.4.2287-2300.2005 |
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