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Genome Packaging Sense Is Controlled by the Efficiency of the Nick Site in the Right-End Replication Origin of Parvoviruses Minute Virus of Mice and LuIII

The parvovirus minute virus of mice (MVM) packages predominantly negative-sense single strands, while its close relative LuIII encapsidates strands of both polarities with equal efficiency. Using genomic chimeras and mutagenesis, we show that the ability to package positive strands maps not, as orig...

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Bibliografiska uppgifter
Huvudupphovsmän: Cotmore, Susan F., Tattersall, Peter
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2005
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC546602/
https://ncbi.nlm.nih.gov/pubmed/15681430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.4.2287-2300.2005
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