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Genome Packaging Sense Is Controlled by the Efficiency of the Nick Site in the Right-End Replication Origin of Parvoviruses Minute Virus of Mice and LuIII

The parvovirus minute virus of mice (MVM) packages predominantly negative-sense single strands, while its close relative LuIII encapsidates strands of both polarities with equal efficiency. Using genomic chimeras and mutagenesis, we show that the ability to package positive strands maps not, as orig...

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Detalhes bibliográficos
Main Authors: Cotmore, Susan F., Tattersall, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC546602/
https://ncbi.nlm.nih.gov/pubmed/15681430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.4.2287-2300.2005
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