Atomic Resolution Structure of the Oncolytic Parvovirus LuIII by Electron Microscopy and 3D Image Reconstruction

LuIII, a protoparvovirus pathogenic to rodents, replicates in human mitotic cells, making it applicable for use to kill cancer cells. This virus group includes H-1 parvovirus (H-1PV) and minute virus of mice (MVM). However, LuIII displays enhanced oncolysis compared to H-1PV and MVM, a phenotype map...

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Détails bibliographiques
Publié dans:Viruses
Auteurs principaux: Pittman, Nikéa, Misseldine, Adam, Geilen, Lorena, Halder, Sujata, Smith, J. Kennon, Kurian, Justin, Chipman, Paul, Janssen, Mandy, Mckenna, Robert, Baker, Timothy S., D’Abramo, Anthony, Cotmore, Susan, Tattersall, Peter, Agbandje-McKenna, Mavis
Format: Artigo
Langue:Inglês
Publié: MDPI 2017
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5707528/
https://ncbi.nlm.nih.gov/pubmed/29084163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v9110321
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