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Optimizing the Targeting of Mouse Parvovirus 1 to Murine Melanoma Selects for Recombinant Genomes and Novel Mutations in the Viral Capsid Gene

Combining virus-enhanced immunogenicity with direct delivery of immunomodulatory molecules would represent a novel treatment modality for melanoma, and would require development of new viral vectors capable of targeting melanoma cells preferentially. Here we explore the use of rodent protoparvovirus...

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Detalhes bibliográficos
Publicado no:Viruses
Main Authors: Marr, Matthew, D’Abramo, Anthony, Pittman, Nikea, Agbandje-McKenna, Mavis, Cotmore, Susan, Tattersall, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5850361/
https://ncbi.nlm.nih.gov/pubmed/29385689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v10020054
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