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Structural Characterization of H-1 Parvovirus: Comparison of Infectious Virions to Empty Capsids
The structure of single-stranded DNA (ssDNA) packaging H-1 parvovirus (H-1PV), which is being developed as an antitumor gene delivery vector, has been determined for wild-type (wt) virions and noninfectious (empty) capsids to 2.7- and 3.2-Å resolution, respectively, using X-ray crystallography. The...
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| Auteurs principaux: | , , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society for Microbiology
2013
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3624314/ https://ncbi.nlm.nih.gov/pubmed/23449783 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03416-12 |
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