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Erythrocyte sialoglycoproteins engage Siglec-9 on neutrophils to suppress activation

Healthy blood neutrophils are functionally quiescent in the bloodstream, have a short lifespan, and exit the circulation to carry out innate immune functions, or undergo rapid apoptosis and macrophage-mediated clearance to mitigate host tissue damage. Limitation of unnecessary intravascular neutroph...

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Detalhes bibliográficos
Publicado no:Blood
Main Authors: Lizcano, Anel, Secundino, Ismael, Döhrmann, Simon, Corriden, Ross, Rohena, Cristina, Diaz, Sandra, Ghosh, Pradipta, Deng, Lingquan, Nizet, Victor, Varki, Ajit
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5465837/
https://ncbi.nlm.nih.gov/pubmed/28416510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2016-11-751636
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