The G protein G(i1) exhibits basal coupling but not preassembly with G protein-coupled receptors

The G(i/o) protein family transduces signals from a diverse group of G protein-coupled receptors (GPCRs). The observed specificity of G(i/o)-GPCR coupling and the high rate of G(i/o) signal transduction have been hypothesized to be enabled by the existence of stable associates between G(i/o) protein...

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Vydáno v:J Biol Chem
Hlavní autoři: Bondar, Alexey, Lazar, Josef
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2017
Témata:
Signal Transduction
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5465492/
https://ncbi.nlm.nih.gov/pubmed/28438833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.768127
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