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Dissociated Gα(GTP) and Gβγ Protein Subunits Are the Major Activated Form of Heterotrimeric Gi/o Proteins
Although most heterotrimeric G proteins are thought to dissociate into Gα and Gβγ subunits upon activation, the evidence in the Gi/o family has long been inconsistent and contradictory. The Gi/o protein family mediates inhibition of cAMP production and regulates the activity of ion channels. On the...
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Main Authors: | , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Society for Biochemistry and Molecular Biology
2014
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3894313/ https://ncbi.nlm.nih.gov/pubmed/24307173 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.493643 |
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