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Dissociated Gα(GTP) and Gβγ Protein Subunits Are the Major Activated Form of Heterotrimeric Gi/o Proteins

Although most heterotrimeric G proteins are thought to dissociate into Gα and Gβγ subunits upon activation, the evidence in the Gi/o family has long been inconsistent and contradictory. The Gi/o protein family mediates inhibition of cAMP production and regulates the activity of ion channels. On the...

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Bibliografiset tiedot
Päätekijät: Bondar, Alexey, Lazar, Josef
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Biochemistry and Molecular Biology 2014
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3894313/
https://ncbi.nlm.nih.gov/pubmed/24307173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.493643
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