Gene conversion and evolution of Xq28 duplicons involved in recurring inversions causing severe hemophilia A
Inversions breaking the 1041 bp int1h-1 or the 9.5-kb int22h-1 sequence of the F8 gene cause hemophilia A in 1/30,000 males. These inversions are due to homologous recombination between the above sequences and their inverted copies on the same DNA molecule, respectively, int1h-2 and int22h-2 or int2...
Zapisane w:
| Wydane w: | Genome Res |
|---|---|
| Główni autorzy: | , , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Cold Spring Harbor Laboratory Press
2005
|
| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC546521/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15687285/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gr.2946205 |
| Etykiety: |
Nie ma etykietki, Dołącz pierwszą etykiete!
|