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Drug Discovery Targeting Bromodomain-Containing Protein 4

[Image: see text] BRD4, the most extensively studied member of the BET family, is an epigenetic regulator that localizes to DNA via binding to acetylated histones and controls the expression of therapeutically important gene regulatory networks through the recruitment of transcription factors to for...

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Détails bibliographiques
Publié dans:J Med Chem
Auteurs principaux: Liu, Zhiqing, Wang, Pingyuan, Chen, Haiying, Wold, Eric A., Tian, Bing, Brasier, Allan R., Zhou, Jia
Format: Artigo
Langue:Inglês
Publié: American Chemical Society 2017
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5464988/
https://ncbi.nlm.nih.gov/pubmed/28195723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jmedchem.6b01761
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