Immunosuppressive tumor-infiltrating myeloid cells mediate adaptive immune resistance via a PD-1/PD-L1 mechanism in glioblastoma

BACKGROUND. Adaptive immune resistance in the tumor microenvironment appears to attenuate the immunotherapeutic targeting of glioblastoma (GBM). In this study, we identified a tumor-infiltrating myeloid cell (TIM) population that expands in response to dendritic cell (DC) vaccine treatment. The aim...

詳細記述

保存先:
書誌詳細
出版年:Neuro Oncol
主要な著者: Antonios, Joseph P., Soto, Horacio, Everson, Richard G., Moughon, Diana, Orpilla, Joey R., Shin, Namjo P., Sedighim, Shaina, Treger, Janet, Odesa, Sylvia, Tucker, Alexander, Yong, William H., Li, Gang, Cloughesy, Timothy F., Liau, Linda M., Prins, Robert M.
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 2017
主題:
Basic and Translational Investigation
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5464463/
https://ncbi.nlm.nih.gov/pubmed/28115578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/now287
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