Inhibition of glioblastoma tumorspheres by combined treatment with 2-deoxyglucose and metformin

BACKGROUND. Deprivation of tumor bioenergetics by inhibition of multiple energy pathways has been suggested as an effective therapeutic approach for various human tumors. However, this idea has not been evaluated in glioblastoma (GBM). We hypothesized that dual inhibition of glycolysis and oxidative...

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Dettagli Bibliografici
Pubblicato in:Neuro Oncol
Autori principali: Kim, Eui Hyun, Lee, Ji-Hyun, Oh, Yoonjee, Koh, Ilkyoo, Shim, Jin-Kyoung, Park, Junseong, Choi, Junjeong, Yun, Mijin, Jeon, Jeong Yong, Huh, Yong Min, Chang, Jong Hee, Kim, Sun Ho, Kim, Kyung-Sup, Cheong, Jae-Ho, Kim, Pilnam, Kang, Seok-Gu
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2017
Soggetti:
Basic and Translational Investigations
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5464255/
https://ncbi.nlm.nih.gov/pubmed/27571886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/now174
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