Inhibition of glioblastoma tumorspheres by combined treatment with 2-deoxyglucose and metformin

BACKGROUND. Deprivation of tumor bioenergetics by inhibition of multiple energy pathways has been suggested as an effective therapeutic approach for various human tumors. However, this idea has not been evaluated in glioblastoma (GBM). We hypothesized that dual inhibition of glycolysis and oxidative...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Kim, Eui Hyun, Lee, Ji-Hyun, Oh, Yoonjee, Koh, Ilkyoo, Shim, Jin-Kyoung, Park, Junseong, Choi, Junjeong, Yun, Mijin, Jeon, Jeong Yong, Huh, Yong Min, Chang, Jong Hee, Kim, Sun Ho, Kim, Kyung-Sup, Cheong, Jae-Ho, Kim, Pilnam, Kang, Seok-Gu
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
Assuntos:
Basic and Translational Investigations
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5464255/
https://ncbi.nlm.nih.gov/pubmed/27571886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/now174
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