Inhibition of glioblastoma tumorspheres by combined treatment with 2-deoxyglucose and metformin

BACKGROUND. Deprivation of tumor bioenergetics by inhibition of multiple energy pathways has been suggested as an effective therapeutic approach for various human tumors. However, this idea has not been evaluated in glioblastoma (GBM). We hypothesized that dual inhibition of glycolysis and oxidative...

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Bibliografske podrobnosti
izdano v:Neuro Oncol
Main Authors: Kim, Eui Hyun, Lee, Ji-Hyun, Oh, Yoonjee, Koh, Ilkyoo, Shim, Jin-Kyoung, Park, Junseong, Choi, Junjeong, Yun, Mijin, Jeon, Jeong Yong, Huh, Yong Min, Chang, Jong Hee, Kim, Sun Ho, Kim, Kyung-Sup, Cheong, Jae-Ho, Kim, Pilnam, Kang, Seok-Gu
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2017
Teme:
Basic and Translational Investigations
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5464255/
https://ncbi.nlm.nih.gov/pubmed/27571886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/now174
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