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P14.01 MTHFR genotype may affect methotrexate toxicity, survival and disease occurrence in patients with central nervous system lymphoma

Introduction: Two common methylenetetrahydrofolate reductase (MTHFR) single nucleotide polymorphisms (SNPs) - C677T and A1298C - have been implicated in MTX toxicity in patients receiving high dose methotrexate (HD-MTX) therapy. Our objective was to explore whether MTHFR polymorphisms are associated...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Neuro Oncol
Egile Nagusiak: Ali, A., Aregawi, D.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Oxford University Press 2017
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5463754/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox036.388
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