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Meta-analysis of methylenetetrahydrofolate reductase (MTHFR) polymorphisms affecting methotrexate toxicity
OBJECTIVE: Methotrexate is an effective therapy for Rheumatoid Arthritis (RA) but is also associated with toxicity. Pharmacogenetics is the systematic evaluation of the role of genetic differences in the efficacy and toxicity of therapeutic interventions. Because the results of small pharmacogenetic...
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| Main Authors: | , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2009
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2673494/ https://ncbi.nlm.nih.gov/pubmed/19208607 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3899/jrheum.080576 |
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