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P14.01 MTHFR genotype may affect methotrexate toxicity, survival and disease occurrence in patients with central nervous system lymphoma
Introduction: Two common methylenetetrahydrofolate reductase (MTHFR) single nucleotide polymorphisms (SNPs) - C677T and A1298C - have been implicated in MTX toxicity in patients receiving high dose methotrexate (HD-MTX) therapy. Our objective was to explore whether MTHFR polymorphisms are associated...
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| Publicado no: | Neuro Oncol |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5463754/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox036.388 |
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