The accumulation of MMS-induced single strand breaks in G(1) phase is recombinogenic in DNA polymerase β defective mammalian cells

DNA polymerase (Pol) β null mouse embryonic fibroblasts provide a useful cell system to investigate the effects of alterations in base excision repair (BER) on genome stability. These cells are characterized by hypersensitivity to the cytotoxic effects of methyl methanesulfonate (MMS) and by decreas...

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Detaylı Bibliyografya

Yayımlandı:	Nucleic Acids Res
Asıl Yazarlar:	Pascucci, Barbara, Russo, Maria Teresa, Crescenzi, Marco, Bignami, Margherita, Dogliotti, Eugenia
Materyal Türü:	Artigo
Dil:	Inglês
Baskı/Yayın Bilgisi:	Oxford University Press 2005
Konular:	Article
Online Erişim:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC546155/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15647510/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/gki168
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